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Mesothelioma

Construction workers, industrial workers, military veterans and others who worked with asbestos-contaminated products are at risk of developing mesothelioma. Exposure to asbestos fibers repeatedly leads to chronic inflammation that damages mesothelium, causing DNA changes.

The risk of malignant mesothelioma increasing with cumulative exposure and up to the third or fourth power of time since the first exposure. It could take between 10 and 50 years after the exposure for symptoms to manifest.

Symptoms

The mesothelium is the cells that cover the body. The mesothelium lining protects organs as well as other tissue by lubricating them so that they can slide across each other easily. Malignant mesothelioma may be spread to various areas of the body and affect the lungs, heart and abdomen. Other symptoms include fatigue and chest pain.

The symptoms of mesothelioma may take anywhere from 10 to 50 years to appear and make it difficult for doctors to diagnose the disease. It is also possible to mistake for other diseases, like pneumonia or flu.

Patients may experience symptoms like chest pain, breathing problems or the rubbing of the nails and fingers. Patients with mesothelioma may also develop an accumulation of fluid in the chest (peritoneal) or belly. This condition is known as a pleural effusion.

Like lung cancer, mesothelioma is not evident on imaging tests, like an X-ray or CT scan until the cancer has advanced over a period of time. Often, doctors need to conduct a biopsy to confirm the mesothelioma diagnosis. This can be done with bronchoscopy or a needle biopsy.

These diagnostic procedures help doctors diagnose mesothelioma, and then determine the best treatment plan for the patient. Doctors can examine a patient's asbestos exposure history to determine if he or she has a risk of developing asbestos compensation-related diseases.

The greatest risk is for workers exposed to asbestos in their workplaces. Workers at high-risk occupations include those working in shipbuilding, construction and other blue-collar industries and veterans of the United States Armed Forces. People who live with asbestos-exposed workers also are at risk of mesothelioma, particularly if the worker brings home asbestos fibers on their clothing.

Patients who have been diagnosed with mesothelioma could benefit from regularly visiting their physician for a checkup, and also talking about any health concerns related to asbestos. This is important since mesothelioma could be misinterpreted as a different disease like asbestosis.

Diagnosis

The initial symptoms of mesothelioma can look like the flu, pneumonia or intestinal trouble. The long time of latency means patients may experience symptoms for 10 - 50 years after exposure to asbestos. The fact that it is similar to other diseases also makes it hard to recognize. The location of the body part affected may also influence the symptoms.

The first step is to see a primary care doctor or a different doctor who can pinpoint the source of your symptoms. They will ask for an entire medical history and check to determine if exposure to asbestos has been mentioned. They will also perform physical examinations and carry out basic tests, such as blood work or Xrays.

A biopsy may be required to confirm a diagnosis, dependent on the type of mesothelioma. The procedure involves inserting a needle in the chest or abdomen to collect a small amount of the tissue. The tissue is then examined in a lab to search for cancerous mesothelioma cells. Mesothelioma cancer cells can be epithelioid or sarcomatoid. Both types are malignant. Epithelioid mesothelioma makes up 70 percent of mesothelioma cases while sarcomatoid mesothelioma makes up the remainder.

After a mesothelioma biopsied procedure has been done, doctors can develop an action plan. They typically refer the patient to a specialist for advice on the most effective treatment for their particular condition.

Mesothelioma can be caused by the exposure to asbestos fibers that are microscopic. Asbestos is made up of a group minerals that look like bundles of thin, tiny fibers. They are found in rocks and soil and are typically released into the air during mining, construction and other activities. Inhaling fibers can cause inflammation in the lungs. In time, this may result in scarring (asbestosis) and eventually mesothelioma. The cancer usually occurs in the lung. However, it can also develop in the linings of the stomach (peritoneal pericardial) or in the testicles.

Treatment

Mesothelioma is a form of cancer that is an abnormal growth of cells that invades the surrounding organs and tissues. Cancerous cells may also expand to other parts of the body via the lymphatic system or bloodstream.

Mesothelioma treatment options differ based on the nature and location of mesothelioma. Doctors are currently using surgery and chemotherapy to treat mesothelioma. Radiation therapy can be used in conjunction with surgery or chemotherapy. It is designed to kill cancerous cells and decrease the pain and swelling associated mesothelioma.

Asbestos exposure may cause asbestosis. This is a non-cancerous disease that causes scarring in the lungs and other parts of the human body. It can also lead to mesothelioma, a more serious form of asbestos case-related illness which is typically fatal. Mesothelioma, an aggressive cancer typically affects the abdomen and lungs. It can cause breathing problems, coughing and chest pain. X-rays or CT scans can detect mesothelioma. The results of CT scans highlight areas of greater density, which could indicate scar tissue or a tumor. Doctors can perform a needle biopsy or bronchoscopy to determine the difference.

A bronchoscopy is done by inserting a thin, flexible tube into the respiratory passages in order to see the tissue and take samples for testing. A needle biopsy involves injecting liquid into the area in order to remove a small amount of tissue for testing. Both procedures are painful, but the results can help doctors identify asbestosis and mesothelioma.

Mesothelioma symptoms can be compared to the symptoms of other diseases and can take as long as 50 years to develop following the initial exposure. The latency period between exposure to asbestos and the onset of symptoms can make it difficult to determine the disease. People are often mistakenly diagnosed as having other illnesses, such as pneumonia or flu.

Scientists don't know for sure what causes mesothelioma but they do know that exposure to asbestos increases the risk. Asbestos can be exposed through industries like asbestos mining, manufacturing and construction. As well, asbestos legal-containing products are often carried by workers to homes and other workplaces where fibers are ingested or inhaled. Amphibole asbestos fibers and snakeine asbestos are the most prevalent kinds of asbestos found in mesothelioma. The type of asbestos known as serpentine is less cancerous than the amphibole type, however both are capable of causing illness.

Prognosis

Mesothelioma is a rare cancer that affects the thin layer of tissue lining internal organs. It usually develops due to exposure to asbestos, a class of minerals that are hard and resistant to heat. It is believed that asbestos fibers enter the lungs, irritate the membranes, and eventually cause cancer. This irritation can cause genetic mutations that can lead to tumour growth.

The exposure to asbestos can happen in many ways, such as mining, manufacturing, repairing or cleaning asbestos-containing products. You can also be exposed at home through wearing or washing someone else's asbestos-containing clothing. Certain people are at greater risk of developing mesothelioma because of their relatives' history of the disease or a predisposition to it due to other factors like genetics.

Mesothelioma patients may experience a number of symptoms, and they often resemble other illnesses. It can be difficult for doctors diagnose mesothelioma in its early stages. It is crucial that people who have been exposed asbestos be honest with their doctor and ask for regular checks.

The majority of cases of mesothelioma are caused by occupational Asbestos Legal exposure. Studies have proven that exposure to asbestos can also cause mesothelioma. This is due to the fact that asbestos dust can move from work sites to other areas in the area where people live. Mesothelioma is more frequent in people who live within 2000 meters of an asbestos mine or cement plant.

Some patients with mesothelioma are diagnosed with a lung condition called asbestosis before their mesothelioma begins. Asbestosis can cause the lungs to become thicker and make it difficult for people to breathe. People with this condition are more likely to require oxygen at home, and may need to undergo lung surgeries like lung lobectomy.

Some people with mesothelioma also receive treatment for their symptoms. People with mesothelioma may be given drugs to help breathe, or they may participate in clinical trials for treatments that are experimental. Mesothelioma is still a lethal cancer, but early detection and treatment can improve the prognosis. Patients who have undergone multiple cycles of chemotherapy and surgery have been able extend their lives for up to 10 years.